商品编号


F6111



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


Inhibitors



Size

25 mg


商品信息

LY294002 is a selective phosphatidylinositol 3-kinase (PI3K) inhibitor. LY294002 inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation.


Additional Information






Product Name:

LY294002



Also Known As:

2-morpholin-4-yl-8-phenylchromen-4-one



Catalog No.:

F6111



Size:

25 mg



Molecular Weight:

307.34 Da



Species:

N/A



Source:

Synthetic



Stock:

Powder



Concentration:

N/A



Quality Assurance:

>99% by HPLC and NMR



Storage:

Elig
IBL
e for room temperature shipping. Store at -20°C upon receiving; protect from air and light



PDF Data Sheet:

PDF Datasheet



NCBI RefSeq:

N/A



Image(s):

(Click image to enlarge)

Purity check of Necrostatin-1 by HPLC



Shipping Method:

Room temperature shipping



References:

1. Vlahos CJ,
et al
. (1994) Journal of
BIOLOG
ical Chemistry 269 (7): 5241–5248.
2. Blommaart EF,
et al
. (1997) Eur. J. Biochem. 243: 240–246.
3. Maira SM,
et al
. (2009) Biochem Soc Trans. 37(Pt 1):265-72.




Details

LY294002 is a selective phosphatidylinositol 3-kinase (PI3K) inhibitor. LY294002 inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation.

How to use
LY294002 was used at 1-10 uM in cell-based in vitro assays.
Images
(Click image to enlarge)

Purity check of Necrostatin-1 by HPLC