商品编号


H8900



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


Deubiquitinating Enzymes



Size

25 ?g

商品信息

MINDY-1 (FAM63A) is a deubiquitinase that contains a tandem motif interacting with ubiquitin (MIU) that selectively binds lysine 48-linked polyubiquitin. MINDY-1 prefers to cleave lysine 48-linked long polyubiquitin chains.


Additional Information






Product Name:

MINDY-1



Also Known As:

MINDY1, FAM63A



Catalog No.:

H8900



Size:

25 ?g



Molecular Weight:

51.8 kDa



Species:

Human



Source:

E. coli



Stock:

20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol



Concentration:

See tube label



Quality Assurance:

>90% by SDS-PAGE, see datasheet for gel image



Storage:

Store at -80°C; avoid multiple freeze-thaw cycles



PDF Data Sheet:

PDF Datasheet
，
MSD
S



NCBI RefSeq:

NM_001319998.1



Image(s):

H8900 image

A. Coomassie stained SDS-PAGE of 5 ug Mindy-1. B. Deubiquitination of 5 ug K48 polyUb chain mix or K63 polyUb chain mix by 0.5 uM Mindy-1 in 1X DUB buffer II. Reactions were stopped after 2h incubation.




Shipping Method:

Dry ice shipping



References:

1. Kristariyanto YA.,
et al
. (2017) EMBO Report 18, 392.
2. Rehman SAA.,
et al
. (2016) Mol. Cell 63, 143.




Details

MINDY-1 (FAM63A) is a deubiquitinase that contains a tandem motif interacting with ubiquitin (MIU) that selectively binds lysine 48-linked polyubiquitin. MINDY-1 prefers to cleave lysine 48-linked long polyubiquitin chains.