商品编号


H3110



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


Deubiquitinating Enzymes



Size

25 ?g

商品信息

OTB2; OTU2; C14orf137

Additional Information






Product Name:

GST-OTUB2



Also Known As:

N/A



Catalog No.:

H3110



Size:

25 ?g



Molecular Weight:

27.2 kDa



Species:

Human



Source:

Bacterial recombinant



Stock:

20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol



Concentration:

See tube label



Quality Assurance:

~95% by SDS-PAGE, see datasheet for gel image



Storage:

Store at -80°C; avoid multiple freeze-thaw cycles



PDF Data Sheet:

PDF Datasheet
，
MSD
S



NCBI RefSeq:

NM_023112



Image(s):

N/A



Shipping Method:

Dry ice shipping



References:

1. Balakirev MY,
et al.
(2003) EMBO Rep 4(5), 517 – 522.
2. Reyes-Turcu FE,
et al.
(2009) Annu Rev Biochem 78, 363 – 397.
3. Li S,
et al.
(2010) J Biol Chem 285(7), 4291 – 4297.




Details

Deubiquitinating enzymes (DUBs) are proteases that posses the
ABI
lity to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play important roles in regulating various cellular events. OTUB2 is a member of the ovarian tumor domain family. Not much is known about the
BIOLOG
ical function of this enzyme, but it may deubiquitinate TRAF3 and -6. This would negatively regulate virus-triggered type I IFN induction.