商品编号


H1201



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


Deubiquitinating Enzymes



Size

100 ?g

商品信息

Ubiquitin C-terminal hydrolase L3 (UchL3) is a deubiquitinase enzyme (DUB), which performs hydrolysis of the bond at the C terminus of the ubiquitin and trims down the polyubiquitin chain into monomers. UchL3 has been found to also process a ubiquitin-like substrate called NEDD8. It is 52% identical to the amino acid sequence of its related DUB, UchL1, and may share roles in maintaining neurons of the gracile tract in mice.

Additional Information






Product Name:

UCHL3



Also Known As:

UCH-L3



Catalog No.:

H1201



Size:

100 ?g



Molecular Weight:

26.2 kDa



Species:

Human



Source:

Bacterial recombinant



Stock:

20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol



Concentration:

See tube label



Quality Assurance:

~95% by SDS-PAGE, see datasheet for gel image



Storage:

Store at -80°C; avoid multiple freeze-thaw cycles



PDF Data Sheet:

PDF Datasheet
，
MSD
S



NCBI RefSeq:

NM_001270952



Image(s):

N/A



Shipping Method:

Dry ice shipping



References:

1. Pckard CM, Rose IA (1985) J Biol Chem 260(13), 7903 – 7910.
2. Day IN,
et al
. (1990) Biochem J 268(2), 521 – 524. 3. Wilkinson KD,
et al
. (1999) J Mol Biol 291(5), 1067 – 1077.
4. Kwon J (2007) Exp Anim 56(2), 71 – 77.




Details

Ubiquitin C-terminal hydrolase L3 (UchL3) is a deubiquitinase enzyme (DUB), which performs hydrolysis of the bond at the C terminus of the ubiquitin and trims down the polyubiquitin chain into monomers. UchL3 has been found to also process a ubiquitin-like substrate called NEDD8. It is 52% identical to the amino acid sequence of its related DUB, UchL1, and may share roles in maintaining neurons of the gracile tract in mice.