商品编号


K0108S



品牌


Accelagen



公司


Accelagen



公司分类


Kinases



Concentration

1 mg/ml


Size

10 ?g

商品信息


Description:
Human PAK7 kinase (UniProt: Q9P286; NCBI: NM_177990) belongs to a family of p21-activated kinases. These serine/threonine kinases are regulated by the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of
BIOLOG
ical activities. PAK7 (PAK5) is predominantly expressed in brain. It is capable of promoting neurite outgrowth and cell survival. PAK7KD (PAK5KD) is a recombinant wild type human PAK7 kinase domain (amino acids 425–719 of full-length human PAK7) expressed in E. coli and purified to homogeneity with full activity.

Molecular Mass and Phosphorylation:
The calculated mass is 33,934. PAK7KD is fully phosphorylated at S602 and an additional site with a measured mass of 34,096 (2P).

St
ABI
lity and Storage:
Stable at -70
o
C for 12 months from date of receipt. Protein should be thawed on ice. Protein can be flash-frozen in liquid nitrogen and stored at -70
o
C.

Applications:
Enzymatic studies, inhibitor screen, and selectivity profiling
High concentration available for crystallization