商品编号


K0107B



品牌


Accelagen



公司


Accelagen



公司分类


Kinases



Concentration

1 mg/ml


Size

Bulk

商品信息


Description:
Human PAK4 kinase (UniProt: O96013; NCBI: NM_005884) belongs to a family of p21-activated kinases. These serine/threonine kinases are regulated by the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of
BIOLOG
ical activities. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin
Cytoskeleton
. PAK4KD is a recombinant wild type human PAK4 kinase domain (amino acids 300–591 of full-length human PAK4) expressed in E. coli and purified to homogeneity with full activity.

Molecular Mass and Phosphorylation:
The calculated mass is 33,309. PAK4KD is fully phosphorylated at S474 with a measured mass of 33,389 (1P).

St
ABI
lity and Storage:
Stable at -70
o
C for 12 months from date of receipt. Protein should be thawed on ice. Protein can be flash-frozen in liquid nitrogen and stored at -70
o
C.

Applications:
Enzymatic studies, inhibitor screen, and selectivity profiling
High concentration available for crystallization