商品编号


560-11R-50



品牌


Lee Biosolutions



公司


Lee Biosolutions, Inc



公司分类


Proteins / Enzymes



Size

50 ug

商品信息



Description




Product Name

Recombinant Human Thyroid Peroxidase



Source

Baculovirus, Sf9 Cells



Catalogue Number

560-11R



Purity

>
96% (SDS-PAGE)



Form

Liquid



Protein

>
0.5 mg/mL



Form

Solution in Tris HCl, NaCl, KI and glycerol, pH 7.6.



Identity

Confirmed by Western Blot



Recertification

2 years



Storage

-20°C



Additional Info

Full-length protein, no tag sequences or membrane binding domain, and not enzymatically active



Application

Autoimmune capture in commercial assays



Synonyms

r-hTPO, r-TPO,TPO



Molecular Weight

~104,000









Applications


Controls / Calibrators / Standards Immunoassays Assay Development / Validation Life Science




Overview


Human Thyroid peroxidase (TPO) is an enzyme mainly expressed in the thyroid that liberates iodine for addition onto tyrosine residues on Thyroglobulin for the production of thyroxine (thyroid hormone).
Thyroid Peroxidase is the antigenic determinant of the thyroid microsome associated with anti-TPO autoantibodies. Anti-TPO is an important secondary
Marker
in the diagnosis of Grave's and Hashimoto disease. Thyroid antibodies are also assiciated with infertility and fetal loss.
Technical support, bulk quantities and aliquoting available, email Info@leebio.com for more details.