商品编号


AG-40B-0018-3050



品牌


Adipogen



公司


Adipogen



公司分类


Proteins



Size

3 x 50 ?g


商品信息


More Information



Product Details



Synonyms

TRANCE-R; TNFRSF11A; ODFR; Osteoclast Differentiation Factor Receptor; CD265



Product Type

Protein



Properties



Source/Host

HEK 293 cells



Sequence

Human RANK (aa 29-213) is fused at the C-terminus to the Fc portion of human IgG1.



Crossreactivity

Human
Mouse



Specificity

Binds to human and mouse RANKL.



BIOLOG
ical Activity

Inhibits human rhsRANKL
BIOLOG
ical functions.



MW

~55kDa (SDS-PAGE)



Purity

≥95% (SDS-PAGE)



Endotoxin Content

<0.01eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">0.01eu>



Concentration

1mg/ml after reconstitution.



Reconstitution

Reconstitute with 50μl sterile water.



Formulation

Lyophilized. Contains PBS.



Other Product Data

UniProt link Q9Y6Q6: RANK (human) (precursor)




Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
PBS containing at least 0.1% BSA should be used for further dilutions.



Use/St
ABI
lity

Stable for at least 6 months after receipt when stored at -20°C.



Documents



MSD
S


Download PDF



Product Specification Sheet



Datasheet


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RANK (TRANCE-R; CD265) is the receptor for RANKL/TRANCE/OPGL. It is essential for RANKL-mediated osteoclastogenesis and is involved in the regulation of interactions between T cells and dendritic cells.