商品编号


YIF-LF-P0005



品牌


Adipogen



公司


Adipogen



公司分类


Proteins



Size

0.5 mg

商品信息


More Information



Product Details



Synonyms

Aop1; AOP-1; Prdx3; PRX III; Protein MER5; EC=1.11.1.15; Perioredoxin-3; Antioxidant Protein 1; Thioredoxin-dependent Peroxide Reductase, Mitochondrial



Product Type

Protein



Properties



Source/Host

E. coli



Crossreactivity

Mouse



BIOLOG
ical Activity

0.9U/mg (One unit will cause the oxidation of 1.0 μmole of NADPH at 25°C at pH7.5)



Purity

≥95% (SDS-PAGE)



Concentration

1 mg/ml



Formulation

Liquid in 20mM HEPES, pH 7.0, 10% Glycerol.



Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.



Declaration

Manufactured by AbFrontier



Shipping and Handling



Shipping

DRY ICE



Short Term Storage

-20°C



Long Term Storage

-80°C



Handling Advice

Avoid freeze/thaw cycles.



Documents



MSD
S

No



Product Specification Sheet



Datasheet


Download PDF





Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx 6 belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20 - 30 kilodalton in molecular size and vary in subcellular localization: Prx 1, 2, and 4 in cytosol, Prx 3 in mitochondria, Prx 4 in ER and secretion, Prx 5 showing complicated distribution including peroxisome, mitochondria and cytosol (1).


Product References
1) Wood, Z. A. et al. (2003) Trends Biochem Sci. 28(1):32-40. (General)