商品编号


YIF-LF-P0053



品牌


Adipogen



公司


Adipogen



公司分类


Proteins



Size

0.2 mg

商品信息


More Information



Product Details



Synonyms

NSE; ENO2; Enolase 2; EC=4.2.1.11; γ-Enolase; Neural Enolase; Neuron-specific Enolase; 2-Phospho-D-Glycerate Hydro-lyase



Product Type

Protein



Properties



Source/Host

E. coli



Crossreactivity

Human



Purity

≥95% (SDS-PAGE)



Formulation

Lyophilized from 20mM HEPES, pH7.0.



Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.



Declaration

Manufactured by AbFrontier



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

Avoid freeze/thaw cycles.



Use/St
ABI
lity

After reconstitution, store at -80°C.



Documents



MSD
S

No



Product Specification Sheet



Datasheet


Download PDF





Enolase (2-phosphoglycerate hydrolyase or phosphopyruvate hydrates) is a glycolytic enzyme that catalyzes the dehydration and conversion of 2-phosphoglycerate to phosphoenolpyruvate. It comprises three distinct subunits, α, β and γ. The γγ and αγ dimeric forms of enolase, referred to as neuron-specific enolase (NSE), are localized mainly in neurons and neuroectodermal tissue. NSE has a high st
ABI
lity in
BIOLOG
ical fluids and can easily diffuse to the extracellular medium and cerebrospinal fluid (CSF) when neuronal membranes are injured. NSE is used clinically as a sensitive and useful
Marker
of neuronal damage in several neurological disorders including stroke, hypoxic brain damage, status epilepticus, Creutzfeldt-Jakob disease, and herpetic encephalitis.


Product References
1) Fletcher, L. et al. (1976) Biochim. Biophys. Acta. 452(1), 245-252. (General)
2) Lima, J.E. et al. (2004) J. Neurol. Sci. 217(1), 31-35. (General)
3) Suzuki, Y. et al. (1999) Neurology 53(8), 1761-1764. (General)