商品编号


YIF-LF-P0012



品牌


Adipogen



公司


Adipogen



公司分类


Proteins



Size

0.5 mg

商品信息


More Information



Product Details



Synonyms

SelX; SEPX1; MsrB1; MSRB1; HSPC270; EC=1.8.4.-; Selenoprotein X; Methionine-R-Sulfoxide Reductase B1



Product Type

Protein



Properties



Source/Host

E. coli



Crossreactivity

Human



Purity

≥95% (SDS-PAGE)



Formulation

Lyophilized from 20mM HEPES, pH 7.4.



Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.



Declaration

Manufactured by AbFrontier



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

Avoid freeze/thaw cycles.



Use/St
ABI
lity

After reconstitution, store at -80°C.



Documents



MSD
S

No



Product Specification Sheet



Datasheet


Download PDF





Methionine sulfoxide reductase B (MsrB), also known as SelX, is a selenoprotein. The oxidation of methionine at the sulfur atom leads to alternative epimers: R form of Met(O) and S form of Met(O). MsrB can reduce R form of both free and protein-incorporated methionine sulfoxide to methionine. It has a crucial role in protecting cells against oxidative damages. MsrA reduces only the S epimer of Met(O), and MsrB reduces the R epimer of Met(O) in proteins. Although the catalytic mechanisms of MsrA and MsrB are similar, two Msrs have no sequence identity and no structural similarity.


Product References
1) Zheung, D. et al. (2003) J. Biomol. NMR, 27, 183-184. (General)
2) Weissbach, H. (2002) Arch.Biochem.Biophys. 397(2), 172-178. (General)
3) Kryukov, G. (2002) Proc.Natl.Acad.Sci.U.S.A. 99(7), 4245-4250. (General)