您好,欢迎您来到格朗瑞生物科技公司网站!
[登录]
[注册]
  • Content

Adipogen/anti-Superoxide Dismutase 4, mAb (3A1)/YIF-LF-MA0042/100 µl

一抗
Adipogen/anti-Superoxide Dismutase 4, mAb (3A1)/YIF-LF-MA0042/100 µl


商品编号


YIF-LF-MA0042



品牌


Adipogen



公司


Adipogen



公司分类


Antibodies



Size

100 µl

商品信息


More Information



Product Details



Synonyms

CCS; Superoxide Dismutase Copper Chaperone; Copper Chaperone for Superoxide Dismutase



Product Type

Monoclonal Antibody



Properties



Clone

3A1



Isotype

Mouse IgG2a κ



Immunogen/Antigen

Recombinant human protein purified from E. coli.



Application


ELISA
Western Blot (1:2,000)
Immunoprecipitation (2 μl)
IHC-P



Crossreactivity

Human



Purity Detail

Ammonium sulfate precipitation.



Formulation

Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.



Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.



Declaration

Manufactured by AbFrontier



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Use/St
ABI
lity

Stable for at least 1 year after receipt when stored at -20°C.



Documents



MSD
S

No



Product Specification Sheet



Datasheet


Download PDF





Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide r
ADI
cal anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3) (1). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit (2). The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain (3). SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways (4). SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. Delivers copper to copper zinc superoxide dismutase (SOD1).


Product References
1) Kuninaka, S. et al. (2000) Br. J. Cancer. 83, 928-934. (General)
2) Strange, R. W. et al. (2003) J. Mol. Biol. 328, 877-891. (General)
3) Weisiger, R. A., and Fridovich, I. (1973) J. Biol. Chem. 248, 3582-3592. (General)
4) Enghild, J. J. et al. (1999) Biochem J. 317, 51-57. (General)

上一篇 Adipogen/anti-Survival Motor Neuron Protein (human), mAb (7B10)/AG-20T-0003-C200/200 µg  下一篇 MFPI/H1 50cm Vials - 10 Pack/1-1050-10/1 Ea

产品货号:3349.6

3349.6 ¥
11至15个工作日送达