商品编号


91-460



品牌


ProSci



公司


ProSci Inc



公司分类


Recombinant Proteins



Size

0.05 mg

商品信息


Specifications


SPECIES:
Human

SOURCE SPECIES:
Human Cells

SEQUENCE:
His22-Ala650

FUSION TAG:
C-6 His tag

TESTED APPLICATIONS:

APPLICATIONS:
This recombinant protein can be used for
BIOLOG
ical assays. For research use only.




Properties


PURITY:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

PREDICTED MOLECULAR WEIGHT:
71.64 kD

PHYSICAL STATE:
Liquid

BUFFER:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

STORAGE CONDITIONS:
Store at -20?C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.




Additional Info


ALTERNATE NAMES:
Xaa-Pro Aminopeptidase 2, Aminoacylproline Aminopeptidase, Membrane-Bound Aminopeptidase P, Membrane-Bound APP, Membrane-Bound AmP, mAmP, X-Pro Aminopeptidase 2, XPNPEP2

ACCESSION NO.:
O43895

PROTEIN GI NO.:
119632232




Background


Xaa-Pro aminopeptidase 2 (XPNPEP2) belongs to the peptidase M24B family of metalloproteases. Human XPNPEP2 is widely expressed in various tissues, such as kidney, lung, heart, placenta, liver, small intestine and colon. However, it doesn’t express in brain, skeletal muscle, pancreas, spleen, thymus, prostate, testis and ovary. XPNPEP2 is a Homotrimer which binds 2 manganese ions per subunit. The metalloprotease XPNPEP2 may play a role in the inflammatory process and other reactions produced in response to injury or infection and the metabolism of the vasodilator bradykinin.