商品编号


G8104-1 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

1 mg

商品信息

Product ID
G8104
Cas No.
145257-03-0
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Guanylin is a gastrointestinal peptide hormone that activates guanyl cyclase C primarily in intestinal epithelial cells, but also in neurons. Guanylin increases intracellular levels of cGMP and induces natriuresis and diuresis in the kidney. Guanylin inhibits cell proliferation of colonic cells, inducing cell cycle arrest.
Product Info
Cas No.
145257-03-0
Purity
≥95%
Formula
C
60
H
90
N
16
O
22
S
4
Formula Wt.
1515.74
Appearance
White to off white powder
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
G8104 Info Sheet PDF
References
Basu N, Saha S, Khan I, et al. Intestinal cell proliferation and senescence are regulated by receptor guanylyl cyclase C and p21. J Biol Chem. 2014 Jan 3;289(1):581-93. PMID: 24217248.
Fonteles MC, do Nascimento NR. Guanylin peptide family: history, interactions with ANP, and new pharmacological perspectives. Can J Physiol Pharmacol. 2011 Aug;89(8):575-85. PMID: 21815750.
Forte LR, Freeman RH, Krause WJ, et al. Guanylin peptides: cyclic GMP signaling mechanisms. Braz J Med Biol Res. 1999 Nov;32(11):1329-36. PMID: 10559833.