商品编号


P2992-0.5 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

0.5 mg

商品信息

Product ID
P2992
Cas No.
87734-77-8
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Phyllolitorin is a bombesin-related amphibian nonapeptide. Phyllolitorin induces contractions in urinary bladder smooth muscle and may play a role in lung branching morphogenesis. In mammals, phyllolitorin binds the gastrin-releasing peptide (GRP)-preferring bombesin receptor and the neuromedin B-preferring bombesin receptor. Phyllolitorin also elicits grooming and scratching behavior in mammalian animal models.
Product Info
Cas No.
87734-77-8
Purity
≥95%
Formula
C
49
H
69
N
11
O11S
Formula Wt.
1020.24
IUPAC Name
(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-5-oxopyrrolidine-2-carboxamide
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
P2992 Info Sheet PDF
References
Lin JT, Coy DH, Mantey SA, et al. Comparison of the peptide structural requirements for high affinity interaction with bombesin receptors. Eur J Pharmacol. 1995 Dec 27;294(1):55-69. PMID: 8788416.
King KA, Torday JS, Sunday ME. Bombesin and [Leu8]phyllolitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism. Proc Natl Acad Sci U S A. 1995 May 9;92(10):4357-61. PMID: 7753811.
Masui A, Kato N, Itoshima T, et al. Scratching behavior induced by bombesin-related peptides. Comparison of bombesin, gastrin-releasing peptide and phyllolitorins. Eur J Pharmacol. 1993 Jul 20;238(2-3):297-301. PMID: 7691621.
Falconieri Erspamer G, Mazzanti G, Farruggia G, et al. Parallel bioassay of litorin and phyllolitorins on smooth muscle preparations. Peptides. 1984 Jul-Aug;5(4):765-8. PMID: 6494026.