商品编号


P1764-1 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

1 mg

商品信息

Product ID
P1764
Cas No.
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Pep-1 is a cell-penetrating peptide used to carry large conjugated structures across cell membranes. Pep-1 inhibits low molecular weight hyaluronan binding to toll-like receptor 4 (TLR4) and other receptors. Pep-1 also decreases intestinal and colonic length, decreases expression of IGF-1 and epiregulin, and decreases intestinal epithelial cell proliferation in vivo.
Product Info
Purity
≥95%
Formula
C
136
H
195
N
35
O
33
Formula Wt.
2848.23
Appearance
White to off white powder
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
P1764 Info Sheet PDF
References
Meloni BP, Craig AJ, Milech N, et al. The Neuroprotective Efficacy of Cell-Penetrating Peptides TAT, Penetratin, Arg-9, and Pep-1 in Glutamic Acid, Kainic Acid, and In Vitro Ischemia Injury Models Using Primary Cortical Neuronal Cultures. Cell Mol Neurobiol. 2013 Nov 9. [Epub ahead of print]. PMID: 24213248.
Thaete LG, Qu XW, Jilling T, et al. Impact of toll-like receptor 4 deficiency on the response to uterine ischemia/reperfusion in mice. Reproduction. 2013 Apr 29;145(5):517-26. PMID: 23509372.
Riehl TE, Ee X, Stenson WF. Hyaluronic acid regulates normal intestinal and colonic growth in mice. Am J Physiol Gastrointest Liver Physiol. 2012 Aug 1;303(3):G377-88. PMID: 22556141.
Bobone S, Piazzon A, Orioni B, et al. The thin line between cell-penetrating and antimicrobial peptides: the case of Pep-1 and Pep-1-K. J Pept Sci. 2011 May;17(5):335-41. PMID: 21294230.