商品编号


P1955-5 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

5 mg

商品信息

Product ID
P1955
Cas No.
5534-95-2
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Pentagastrin is a synthetic polypeptide that stimulates gastric acid secretion on the gastrointestinal tract in a cholinergic signaling-dependent manner. Pentagastrin inhibits motilin-induced contractions in the stomach in animal models. Pentagastrin also enhances gastric defense by increasing mucus gel thickness, mucosal blood flow, and pHi.
Product Info
Cas No.
5534-95-2
Purity
≥95%
Formula
C
37
H
50
N
7
O
9
S
Formula Wt.
768.79
Chemical Name
(3S)-4-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[3-(2-methylpropoxycarbonylamino)propanoylamino]propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-oxobutanoic acid
IUPAC Name
4-[[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2R)-2-[[(2S)-3-(1H-indol-3-yl)-2-[3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoylamino]propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-oxobutanoic acid
Synonym
Gastrodiagnost, Pentagastrinum, Peptavlon, Petogasrin
Melting Point
229°C
Appearance
White to off-white powder
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
MSD
S
P1955
MSD
S PDF
Info Sheet
P1955 Info Sheet PDF
References
Beckert S, Wolf SC, Farrahi F, et al. TGF-beta3 inhibits pentagastrin-stimulated gastric acid secretion in rats. Med Sci Monit. 2005 Mar;11(3):BR80-3. PMID: 15735558.
Yamamoto O, Matsunaga Y, Shiba Y, et al. Inhibition of motilin-induced phase III contractions by pentagastrin in Heidenhain pouch dogs. J Pharmacol Exp Ther. 1994 Dec;271(3):1471-6. PMID: 7996460.
Nishizaki Y, Guth PH, Kim G, et al. Pentagastrin enhances gastric mucosal defenses in vivo: luminal acid-dependent and independent effects. Am J Physiol. 1994 Jul;267(1 Pt 1):G94-104. PMID: 8048536.
Zwick R, Bowes KL, Daniel EE, et al. Mechanism of action of pentagastrin on the lower esophageal sphincter. J Clin Invest. 1976 Jun;57(6):1644-51. PMID: 932198.