商品编号


E537332-1 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

1 mg

商品信息

Product ID
E537332
Cas No.
2503-13-1
Purity
≥97%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Enniatins are a group of mycotoxins produced by several fungal species. They are cyclic hexadepsipeptides structurally related to beauvericin. They may be found as contaminants in food commodities, particularly in cereal grains. Enniatins are found to have a variety of
BIOLOG
ical activities including insecticidal, antifungal, antibiotic and cytotoxic properties. They have been shown to induce apoptosis in several human cancer cell lines and are gaining interest as potential anticancer drugs.
Product Info
Cas No.
2503-13-1
Purity
≥97%
Formula
C
36
H
63
N
3
O
9
Formula Wt.
681.91
Chemical Name
(3S,9S,12R,15S,18R)-9,15-bis[(2S)-butan-2-yl]-3-[(2R)-butan-2-yl]-4,10,16-trimethyl-6,12,18-tri(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone
IUPAC Name
(3S,6R,9S,12R,15S,18R)-3,9,15-Tri[(2S)-2-butanyl]-6,12,18-triisopropyl-4,10,16-trimethyl-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone
Synonym
Fusafungine, cyclo[N(Me)Ile-D-OVal-N(Me)Ile-DL-OVal-N(Me)aIle-D-OVal]
Melting Point
121-125°C
Solubility
Soluble in ethanol, methanol, DMSO, DMF. Insoluble in water.
Appearance
White powder
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
E537332 Info Sheet PDF
References
Liuzzi VC, Mirabelli V, Cimmarusti MT, et al. Enniatin and beauvericin biosynthesis in Fusarium species: production profiles and structural determinant prediction. Toxins (Basel). 2017 Feb;9(2):45. PMID: 28125067.
Gunter AB, Hermans A, Bosnich W, et al. Protein engineering of Saccharomyces cerevisiae transporter Pdr5p identifies key residues that impact Fusarium mycotoxin export and resistance to inhibition. Micro
BIOLOG
yopen. 2016 Dec;5(6):979-991. PMID: 27263049.
Nazari F, Sulyok M, Kobarfard F, et al. Evaluation of emerging mycotoxins beauvericin, enniatins, fusaproliferin and moniliformin in domestic rice in Iran. Iran J Pharm Res. 2015 Spring;14(2):505-512. PMID: 25901158.
Dornetshuber-Fleiss R, Heilos D, Mohr T, et al. The naturally born fusariotoxin enniatin B and sorafenib exert synergistic activity against cervical cancer in vitro and in vivo. Biochem Pharmacol. 2015 Feb 1;93(3):318-331. PMID: 25557295.