商品编号


E5219-1 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

1 mg

商品信息

Product ID
E5219
Cas No.
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Endothelin-1 is an endogenous peptide ago
NIST
at endothelin A and B (ET-A/B) receptors that exhibits anti-angiogenic and vasoconstrictive activities. Endothelin-1 decreases tube formation and PPARγ expression in pulmonary artery endothelial cells. This peptide also increases expression of IL-18 in osteoblasts, inducing proliferation.
Product Info
Purity
≥95%
Formula
C
109
H
159
N
25
O
32
S
5
Formula Wt.
2491.95
Appearance
White to off white powder
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
MSD
S
E5219
MSD
S PDF
Info Sheet
E5219 Info Sheet PDF
References
Zhong X, Wang H, Huang S. Endothelin-1 induces interleukin-18 expression in human osteoblasts. Arch Oral Biol. 2014 Mar;59(3):289-96. PMID: 24581851.
Osmond JM, Gonzalez Bosc LV, Walker BR, et al. Endothelin-1-induced vasoconstriction does not require intracellular Ca2+ waves in arteries from rats exposed to intermittent hypoxia. Am J Physiol Heart Circ Physiol. 2014 Mar;306(5):H667-73. PMID: 24414066.
Wolf D, Tseng N, Seedorf G, et al. Endothelin-1 decreases endothelial PPARγ signaling and impairs angiogenesis after chronic intrauterine pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2014 Feb;306(4):L361-71. PMID: 24337925.