商品编号


C5772-2.5 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

2.5 mg

商品信息

Product ID
C5772
Cas No.
86784-80-7
Purity
≥98%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Corticotropin-releasing factor (CRF) is an endogenous neuropeptide hormone that is involved in stress responses, depression, anxiety, and other mood disorders. CRF binds CRF receptors, stimulating release of adrenocorticotropic hormone (ACTH), cortisol, dehydroepiandrosterone (DHEA), and β-endorphin. CRF also modulates the duration of pregnancy and stimulates release of dehydroepiandrosterone (DHEA) in the fetal adrenal gland. High levels of CRF may be used as a bio
Marker
to detect Alzheimer’s disease or major depression.
Product Info
Cas No.
86784-80-7
Purity
≥98%
Formula
C
208
H
344
N
60
O
63
S
2
Formula Wt.
4757.49
Synonym
CRF
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
C5772 Info Sheet PDF
References
Lowry CA, Moore FL. Regulation of behavioral responses by corticotropin-releasing factor. Gen Comp Endocrinol. 2006 Mar;146(1):19-27. PMID: 16426606.
Arborelius L, Owens MJ, Plotsky PM, et al. The role of corticotropin-releasing factor in depression and anxiety disorders. J Endocrinol. 1999 Jan;160(1):1-12. PMID: 9854171.
Raadsheer FC, van Heerikhuize JJ, Lucassen PJ, et al. Corticotropin-releasing hormone mRNA levels in the paraventricular nucleus of patients with Alzheimer's disease and depression. Am J Psychiatry. 1995 Sep;152(9):1372-6. PMID: 7653697.
Lederis KP, Okawara Y, Richter D, et al. Evolutionary aspects of corticotropin releasing hormones. Prog Clin Biol Res. 1990;342:467-72. PMID: 2200028.