商品编号


R2514-5 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

5 mg

商品信息

Product ID
R2514
Cas No.
93674-99-8
Purity
≥98%
Description
Product Info
Shipping and Storage
Downloads
References

Description
RGDV is a tetrapeptide that delivers attached compounds to targets such as thrombus or tumor cells; it enhances efficacy of anticancer and anti-aggregation or anti-adhesion compounds. RDGV binds integrins on the surfaces of cells and prevents binding of fibrinogen to platelets.
Product Info
Cas No.
93674-99-8
Purity
≥98%
Formula
C
17
H
31
N
7
O
7
Formula Wt.
445.5
Chemical Name
Arginyl-glycyl-aspartyl-valine
IUPAC Name
(2S)-2-[[(2S)-2-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-3-methylbutanoic acid
Synonym
Rgdv tetrapeptide
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
MSD
S
R2514
MSD
S PDF
Info Sheet
R2514 Info Sheet PDF
References
Jin S, Wang Y, Zhu H, et al. Nanosized aspirin-Arg-Gly-Asp-Val: delivery of aspirin to thrombus by the target carrier Arg-Gly-Asp-Val tetrapeptide. ACS Nano. 2013 Sep 24;7(9):7664-73. PMID: 23931063.
Wang F, Cui C, Ren Z, et al. Preparation and
BIOLOG
ical evaluation of tumor-specific Ara-C
Liposoma
l preparations containing RGDV motif. J Pharm Sci. 2012 Dec;101(12):4559-68. PMID: 23023730.
Zhao M, Wang C, Jiang X, et al. Synthesis of RGD containing peptides and their bioactivities. Prep Biochem Biotechnol. 2002 Nov;32(4):363-80. PMID: 12455829.
Preferred conformations of RGDX tetrapeptides to inhibit the binding of fibrinogen to platelets.
Park HS, Kim C, Kang YK. Biopolymers. 2002 Apr 15;63(5):298-313. PMID: 11877740.