商品编号


R2512-25 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

25 mg

商品信息

Product ID
R2512
Cas No.
99896-85-2
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
RGD is a peptide that delivers attached compounds to targets such as thrombus or tumor cells; it enhances efficacy of anticancer and anti-aggregation or anti-adhesion compounds. RDG binds integrins on the surfaces of cells.
Product Info
Cas No.
99896-85-2
Purity
≥95%
Formula
C
12
H
22
N
6
O
6
Formula Wt.
346.3
Chemical Name
Arginyl-glycyl-aspartic acid
IUPAC Name
(2S)-2-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]butanedioic acid
Appearance
White to off white powder
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
R2512 Info Sheet PDF
References
Guo Z, He B, Jin H, et al. Targeting efficiency of RGD-modified nanocarriers with different ligand intervals in response to integrin αvβ3 clustering.
Biomat
erials. 2014 Apr 30. [Epub ahead of print]. PMID: 24794924.
Li Y, Zheng X, Sun Y, et al. RGD-fatty alcohol-modified docetaxel
liposomes
improve tumor selectivity in vivo. Int J Pharm. 2014 Apr 4;468(1-2):133-141. [Epub ahead of print]. PMID: 24709214.
Zhao M, Wang C, Jiang X, et al. Synthesis of RGD containing peptides and their bioactivities. Prep Biochem Biotechnol. 2002 Nov;32(4):363-80. PMID: 12455829.
Preferred conformations of RGDX tetrapeptides to inhibit the binding of fibrinogen to platelets.
Park HS, Kim C, Kang YK. Biopolymers. 2002 Apr 15;63(5):298-313. PMID: 11877740.