商品编号


C0140-2 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

2 mg

商品信息

Product ID
C0140
Cas No.
57014-02-5
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Calcitonin is an endogenous neuropeptide that exhibits pro-oncogenic, anti-osteoarthritic, and anti-resorptive activities. Calcitonin induces activation of NF-κB, upregulating expression and activity of fibronectin, MMP-1, MMP-2, and MMP-9 and increasing cell growth in osteosarcoma cells. When admi
NIST
ered clinically, calcitonin increases serum NO and urinary CTX-II levels, improving medial femoral condyle osteoarthritis. Calcitonin also inhibits SCDP-induced apoptosis of osteoclasts and increases bone formation and volume.
Product Info
Cas No.
57014-02-5
Purity
≥95%
Formula
C
146
H
241
N
43
O
47
S
2
Formula Wt.
3414.94
Melting Point
220°C. (dec)
Solubility
soluble in water
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
MSD
S
C0140
MSD
S PDF
Info Sheet
C0140 Info Sheet PDF
References
Tsagaraki I, Phenekos C, Tsilibary E, et al. Calcitonin-induced NF-κB activation up-regulates fibronectin expression in MG63 osteosarcoma cells. Anticancer Res. 2013 Nov;33(11):4901-6. PMID: 24222127.
Armagan O, Serin DK, Calisir C, et al. Inhalation therapy of calcitonin relieves osteoarthritis of the knee. J Korean Med Sci. 2012 Nov;27(11):1405-10. PMID: 23166425.
Kuo YJ, Tsuang FY, Sun JS, et al. Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272. PMID: 22792258.