商品编号


T3101-5 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

5 mg

商品信息

Product ID
T3101
Cas No.
24769-58-2
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
Thyrotropin-releasing hormone (TRH) is an endogenous tripeptide that acts as a neurotransmitter and neurohormone. TRH regulates hypothalamic-pituitary-adrenal (HPA) and estrogenic signaling pathways. TRH exhibits immunomodulatory and neuroprotective activities. TRH prevents oxidative stress, caspase-mediated apoptosis, glutamate toxicity, and neuroinflammation. Additionally, TRH stimulates epidermal regeneration in ex vivo models, increasing would healing. TRH activates the TRH receptor.
Product Info
Cas No.
24769-58-2
Purity
≥95%
Formula
C
16
H
22
N
6
O
4
Formula Wt.
362.4
IUPAC Name
(2S)-1-[(2S)-3-(4H-imidazol-4-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]pyrrolidine-2-carboxylic acid
Synonym
TRH; Thyrotropin-releasing factor; TRF; Protirelin; Thyroliberin
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
T3101 Info Sheet PDF
References
Fekete C, Lechan RM. Central Regulation of Pituitary-Thyroid Axis Under Physiological and Pathophysiological Conditions. Endocr Rev. 2013 Dec 4:er20131087. [Epub ahead of print]. PMID: 24423980.
Pekary AE, Sattin A. Increased TRH and TRH-like peptide release in rat brain and peripheral tissues during proestrus/estrus. Peptides. 2013 Dec 1;52C:1-10. PMID: 24296042.
Daimon CM, Chirdon P, Maudsley S, et al. The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases. Am J Alzheimers Dis (Columbia). 2013;1(1). PMID: 24199031.
Meier NT, Haslam IS, Pattwell DM, et al. Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin. PLoS One. 2013 Sep 2;8(9):e73596. PMID: 24023889.