商品编号


A2412-25 mg



品牌


LKT Labs



公司


LKT Laboratories, Inc



公司分类


Peptides



Size

25 mg

商品信息

Product ID
A2412
Cas No.
Purity
≥95%
Description
Product Info
Shipping and Storage
Downloads
References

Description
AGDV is a C-terminal peptide sequence found on fibrinogen that is known as a binding site for glycoprotein IIb/IIIa (integrin αIIbβ3); this binding is required for platelet adhesion and aggregation.
Product Info
Purity
≥95%
Formula
C
14
H
24
N
4
O
7
Formula Wt.
360.37
Shipping and Storage
Store Temp
-20°C
Ship Temp
Ambient
Downloads
Info Sheet
A2412 Info Sheet PDF
References
Srokowski EM, Woodhouse KA. Evaluation of the bulk platelet response and fibrinogen interaction to elastin-like polypeptide coatings. J Biomed Mater Res A. 2014 Feb;102(2):540-51. PMID: 23505204.
Podolnikova NP, Gorkun OV, Loreth RM, et al. A cluster of basic amino acid residues in the gamma370-381 sequence of fibrinogen comprises a binding site for platelet integrin alpha(IIb)beta3 (glycoprotein IIb/IIIa). Biochemistry. 2005 Dec 27;44(51):16920-30. PMID: 16363805.
Liu Q, Rooney MM, Kasirer-Friede A, et al. Role of the gamma chain Ala-Gly-Asp-Val and Aalpha chain Arg-Gly-Asp-Ser sites of fibrinogen in coaggregation of platelets and fibrinogen-coated beads. Biochim Biophys Acta. 1998 Jun 11;1385(1):33-42. PMID: 9630497.