商品编号


CHI-HF-210CX3C-C100



品牌


Adipogen



公司


Adipogen



公司分类


Immunology



Size

100 ?g

商品信息


More Information



Product Details



Synonyms

Fractalkine; Chemokine (C-X3-C Motif) Ligand 1; Neurotactin; SCYD1



Product Type

Protein



Properties



Source/Host

CHO cells



Sequence

The extracellular domain of human CX3CL1 (aa 25-100) is fused to the N-terminus of the Fc region of human IgG1.



Crossreactivity

Human



Purity

≥98% (SDS-PAGE)



Endotoxin Content

<0.06eu mu;g="" protein="" (lal="" test;="" lonza).="">0.06eu>



Reconstitution

Reconstitute at 100μg/ml in sterile PBS.



Formulation

Lyophilized from 0.2μm-filtered solution in PBS.



Other Product Data

NCBI reference AAH01163.1: CX3CL1 (human)



Declaration

Manufactured by Chimerigen.



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

Avoid freeze/thaw cycles.



Use/St
ABI
lity

Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.



Documents



MSD
S

No



Product Specification Sheet



Datasheet


Download PDF





CX3CL1 [Fractalkine] is expressed on TNF-α and IL-1 activated endothelial cells (ECs) and binds to CX3CR1. CX3CL1 can exist in 2 forms, as membrane-anchored or as a shed 95-kDa glycoprotein. The soluble CX3CL1 has potent chemoattractant activity for T cells and monocytes, and the cell surface bound protein, which is induced on activated primary endothelial cells, promotes strong adhesion of those leukocytes. CX3CL1 may play a role in regulating leukocyte adhesion and migration processes at the endothelium.