商品编号


60547



品牌


Bpsbioscience



公司


BPS Bioscience Inc.



公司分类


Immunotherapy



Size

2 vials

商品信息













Background:
GITRL (CD357; AITRL; TNLG2A), a part of the tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18), is mainly expressed on antigen presenting cells. GITRL engages with the GITR receptor as a co-stimulatory signal to promote lymphocyte activation.




Description:
Recombinant CHO-K1 cell constitutively expressing full length human GITRL (NP_005083.2). Surface expression is confirmed by flow cytometry.




Host Cell line:
CHO-K1




Mycoplasma Testing:
This cell line has been screened using the MycoAlert? Mycoplasma Detection Kit (
Lonza
, Cat. # LT07-118) to confirm the absence of Mycoplasma contamination. MycoAlert Assay Control Set (
Lonza
, Cat. # LT07-518) was used as a positive control.




Growth Media:

Thaw Medium 3 (BPS Cat. #60186):
Ham’s F-12 medium (Hyclone # SH30526.01) supplemented with 10% FBS (Life technologies #26140-079), 1% Penicillin/Streptomycin (Hyclone SV30010.01).

Complete Growth Medium:
Thaw Medium 3 (BPS Cat. #60186) ?plus 1 mg/ml G418 (
Thermo
Fisher, Cat. #11811031)

Cells should be grown at 37
°
C with 5% CO2 using Thaw Medium 3 (BPS Cat. #60186) plus 1 mg/ml of G418 (
Thermo
Fisher, Cat. #11811031)




Storage / St
ABI
lity:
Store in liquid nitrogen immediately upon receipt.




Application(s):
This cell line is useful for stimulating human GITR on immune cells, as well as binding assays for GITR.




Notes:

Contact us for pricing.

License Disclosure
:Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit use of this cell line in humans or for therapeutic or drug use. The license does not permit modification of the cell line in any way. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of BPS products to your laboratory. BPS does not warrant the suit
ABI
lity of the cell line for any particular use, and does not accept any li
ABI
lity in connection with the handling or use of the cell line. Modifications of this cell line, transfer to another facility, or commercial use of the cells may require a separate license and additional fees; contact sales@bp
SBI
oscience.com for details. Publications using this cell line should reference BPS Bioscience, Inc., San Diego.




Scientific Category:
Immunotherapy




Product Type:
Cell Line




Data shown is lot-specific.
Contact us
for specific information on other lots.