商品编号


79054



品牌


Bpsbioscience



公司


BPS Bioscience Inc.



公司分类


Immunotherapy



Size

384 reactions

商品信息













Description:
The GITR:GITRL TR-FRET Assay is designed to measure the inhibition of GITR binding to GITRL in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and simple; a sample containing biotinylated GITR, GITRL, anti-His Tb donor, dye-labeled acceptor, and an inhibitor is incubated for two hours. Then, the fluorescence intensity is measured using a fluorescence reader.




UniProt
Q7TS55




Synonym(s):
Glucocorticoid-induced TNFR-Related Protein, Tumor Necrosis Factor Receptor Superfamily member 18, TNFRSF18,




Format:





Instructions for use:
See assay kit data sheet for detailed protocol




Storage / St
ABI
lity:
Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.




Application(s):
Great for screening small molecular inhibitors for drug discovery and HTS applications.




Notes:

1. Lechner, M.G., et al. Immunotherapy. 2011 Nov; 3(11): 1317–1340.

2. Ko, K., et al., J. Exp. Med. 2005; 202(7): 885-891.




Warning(s):
Avoid freeze/thaw cycles




Scientific Category:
Immunotherapy




Product Type:
Assay Kit




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