商品编号


40342



品牌


Bpsbioscience



公司


BPS Bioscience Inc.



公司分类


Bromodomain(s)



Size

384 reactions

商品信息













Description:
The SMARCA2 TR-FRET Assay Kit is designed to measure the inhibition of SMARCA2 (BRM) binding to its substrate in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and simple; a sample containing terbium-labeled donor, dye-labeled acceptor, SMARCA2, substrate, and an inhibitor is incubated for 120 minutes. Then, the fluorescence intensity is measured using a fluorescence reader.




UniProt
P51531




Synonym(s):
SMARCA2, BRM, SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 2, AT-Rich Interaction Domain 1B, ARID1B




Format:

COMPONENTS:





Instructions for use:
See assay kit data sheet for detailed protocol




Storage / St
ABI
lity:
Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.




Application(s):
Great for screening small molecular inhibitors for drug discovery and HTS applications.




Reference(s):
Schiaffino-Ortega, S., et al., 2014. J. Hematol. Oncol. 7:81.




Warning(s):
Avoid freeze/thaw cycles.




Scientific Category:
Bromodomain




Product Type:
Assay kit




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