商品编号


79287



品牌


Bpsbioscience



公司


BPS Bioscience Inc.



公司分类


Immunotherapy



Size

96 reactions

商品信息













Background:
CD38, a differentiation antigen of B lymphocytes, is a type II integral membrane protein. It is also known as ADP-ribosyl cyclase and nicotinamide adenine dinucleotide (NAD) glycohydrolase. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in various cells, including pancreatic ? cells. The major enzymatic activity of CD38 is the hydrolysis of NAD. CD38 is a prognostic bio
Marker
for acute B lymphoblastic leukemia.




Description:
The CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) is designed to measure the glycohydrolase activity of CD38 for screening and profiling applications. The CD38 assay kit comes in a convenient 96-well format, with purified recombinant CD38 enzyme, its substrate N6-etheno-NAD (?-NAD), and CD38 assay buffer for 100 enzyme reactions. In addition, the kit includes the CD38 inhibitor apigenin for use as a control inhibitor.




Synonym(s):
cluster of differentiation 38, cyclic ADP ribose hydrolase




Format:

COMPONENTS:






Instructions for use:
See product datasheet for detailed assay protocol.




Storage / St
ABI
lity:
Up to 6 months from date of receipt, when stored as recommended.




Application(s):
Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.




Reference(s):
Wei, W., et al., World J. Biol. Chem. 2014 5(1):58-67.




Notes:
MATERIALS OR INSTRUMENTS REQUIRED BUT NOT SUPPLIED:
Adjustable micropipettor and sterile tips
Fluorescent microplate reader
Rotating or rocker platform




Scientific Category:
Immunotherapy




Product Type:
Assay Kit




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