商品编号


BD19101



品牌


IBL



公司


IBL,inc



公司分类


Tumor Markers


商品信息

Kit size
100
Method
RIA (Potein)
Incubation time
1 x 15 min, 2 x 10 min, 1 x 1 h
Standard range
100 - 2000 pg/mL B12; 1 - 20 ng/mL Folate
Specimen / Volumes
200 ?L serum, plasma
Substrate / isotope
57Co < 55 kBq; 125I < 110 kBq
Regulatory Status:
EU: CE


Details for:


?
Vitamin B12/Folat RIA

Vitamin B12 and folate deficiencies are two of the three unequivocal nutritional anemias of man, the third being that due to lack of iron. Folate (folic acid) deficiency is present in about one-third of all pregnant women, the vast majority of alcoholics, the majority of people who eat a diet devoid of raw fruits and vegetables or fresh fruit juices, many people with structural or functional damage in the upper third of the small bowel and in a number of other situations. Measurement of folate levels constitutes a direct and reliable means of determining the existence of folate deficiency, and this test should be performed for every patient who has a megaloblastic anemia, as well as every patient who has anemia, hypersegmentation of the granulocytic nuclei, and coincident evidence of iron deficiency. Vitamin B12 is essential for normal folic acid metabolism. It is advisable to determine serum vitamin B12 and red cell folate in addition to serum folate to ascertain that the diagnosis is folate deficiency, for which the proper treatment is folic acid. A low red cell folate can also mean that the patient has primary vitamin B12 deficiency, blocking the
ABI
lity of cells to take up folate, in which case the proper therapy would be vitamin B12 rather than folic acid. Vitamin B12 deficiency is most frequently associated with pernicious anemia, gastric damage, intestinal damage and pure vegetarianism. The only significant dietary sources of vitamin B12 are of animal origin
For concrete data please consult the Instruction for Use in the download box on the right side.