商品编号


4891-025-K



品牌


Trevigen



公司


Trevigen, Inc



公司分类


Apoptosis



Size

2500 Wells

商品信息

Description

The XTT Cell Proliferation Assay (XTT-CPA) is a sensitive kit for the measurement of cell proliferation. Cleavage of the tetrazolium salt to formazan occurs via the succinate-tetrazolium reductase system in the mitochondria of metabolically active cells.

Features:


Allows measurement of cell proliferation, cell vi
ABI
lity or cytotoxicity.

Rapid determination in microplates (no solubilization step as in an MTT assay).

Reproduc
IBL
e and sensitive results.

No r
ADI
oactivity.

Ideal for high throughput assays (no washing or other steps that can cause cell loss and vari
ABI
lity).





Catalog # 4891-025-K includes :



Catalog Number

Description

Qty



4891-025-01

XTT Reagent

1



4891-025-02

XTT Activator

1




?

Akt-Activated Endothelium Constitutes the Niche for Residual Disease and Resistance to Bevacizumab in Ovarian Cancer
Bella S. Guerrouahen, Jennifer Pasquier, N
ADI
ne Abu Kaoud, Mahtab Maleki, Marie-Claude Beauchamp, Amber Yasmeen, Pegah Ghi
ABI
, Raphael Lis, F
ABI
en Vidal, Ahmed Saleh, Walter H. Gotlieb, Shahin Rafii, and Arash Rafii
Mol. Cancer Ther., Dec 2014; 13: 3123 – 3136.
http://mct.aacrjournals.org/cgi/content/abstract/13/12/3123

A Splice Variant of the Human Ion Channel TRPM2 Modulates Neuroblastoma Tumor Growth through Hypoxia-induc
IBL
e Factor (HIF)-1/2{alpha}
Shu-jen Chen, Nicholas E. Hoffman, Santhanam Shanmughapriya, Lei Bao, Kerry Keefer, Kathleen Conrad, Salim Merali, Yoshinori Takahashi, Thomas Abraham, Iwona Hirschler-Laszkiewicz, JuFang Wang, Xue-Qian Zhang, Jianliang Song, Carlos Barrero, Yuguang Shi, Yuka Imamura Kawasawa, Michael Bayerl, Tianyu Sun, Mustafa Barbour, Hong-Gang Wang, Muniswamy Madesh, Joseph Y. Cheung, and Barbara A. Miller
J. Biol. Chem., Dec 2014; 289: 36284 – 36302.
http://www.jbc.org/cgi/content/abstract/289/52/36284

“Depletion of the Human Ion Channel TRPM2 in Neuroblastoma
Demonstrates Its Key Role in Cell Survival through Modulation of
Mitochondrial Reactive Oxygen Species and Bioenergetics”
“Lei Bao, Shu-jen Chen, Kathleen Conrad, Kerry Keefer, Thomas Abraham, John P. Lee, JuFang Wang, Xue-Qian Zhang, Iwona Hirschler-Laszkiewicz, Hong-Gang Wang, Sinisa Dovat, Brian Gans, Muniswamy Madesh, Joseph Y. Cheung, and Barbara A. Miller”
J. Biol. Chem., Nov 2016; 291: 24449 – 24464
http://www.jbc.org/cgi/content/abstract/291/47/24449