商品编号


3450-048-DA



品牌


Trevigen



公司


Trevigen, Inc



公司分类


Cell Based Assays



Size

48 Wells

商品信息

Description

DIVAA
?
Angioreactors are?one centimeter long cylinders that is sealed on one end and houses 20 μl total volume. They are?made of implant-grade silicone and provided sterile. Angioreactors are filled with
Trevigen
’s PathClear? basement membrane extract (BME)* premixed with or without angiogenic-modulating factors and ?implanted subcutaneously in the dorsal flank of nude mice. ?Through the process of angiogenesis, host vascular endothelial cells proceed to invade and grow into the BME, forming vessels in the angioreactor.?The sleek design of the angioreactor provides a standardized platform for reproduc
IBL
e and quantifiable
in vivo
angiogenesis assays. Compared to the plug assay, the angioreactor prevents assay errors due to absorption of the basement membrane extract by the mouse. In addition, the angioreactor uses only a fraction of the materials conserving both BME and test compounds used, and up to four angioreactors may be implanted in each mouse, allowing for greater statistical power. ?These are an essential component of?the Directed In Vivo Angiogenesis Assays (DIVAA
?
).

* The PathClear? designation means:


No bacterial or fungal growth detected after incubation at 37°C for 14 days following
USP
XXIV Chapter 71 sterility test.

Negative by PCR test for: mycoplasma, 17 bacterial and virus strains typically included in mouse antibody production (MAP) testing, plus 13 additional murine infectious agents including LDEV, for a total of 31 organisms and viruses.





Catalog # 3450-048-DA includes :



Catalog Number

Description

Qty



3450-048-02

DIVAA BME

1



3450-048-01

DIVAA Angioreactor

1