商品编号


F20204A



品牌


FormuMax



公司


FormuMax Scientific Inc



公司分类


Ammonium Gradient Liposomes for Active Loading



Size

10 mL

商品信息

PEGylated HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol)
liposomes
with Ammonium Gr
ADI
ent (100nm)

HSPC/CHOL/mPEG-DSPE
liposomes
? with ammonium gr
ADI
ent is the formulator's choice in pharmaceutical/biotech industry for both formulation feasibility studies and
Liposoma
l product development, because HSPC is essentially equivalent to DSPC (HSPC contains?about 85 % DSPC?15% DPPC). The main advantages for using HSPC are its lower cost and avail
ABI
lity of GMP quality raw materials. HSPC material used at
FormuMax
is? from one of the world’s premier lipid vendors.

A drug loaidng battery of 250 mM ammonium sulfate is typically used, however?higher concentrations of?ammonium sulfate is also ues to achieve increased drug lo
ADI
ng capacity and drug?retention.

?

Specifications

Product code:
F20204A

Lipid composition:
HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol)

Mean particle size:
100 nm (95 - 120 nm)

Lipid concentration
: 60 mM(60 - 65 mM)

Hydration buffer (lo
ADI
ng battery):?
250 mM ammonium sulfate

External solution:
?10% sucrose, 20mM sodium PO4, pH 6.5 ± 0.2

Shelf-life:
?6 months

Storage:
?2-8?°C, do not freeze

?

HSPC:
hydrogenated phosphatidylcholine (Soy)

CHOL:
cholesterol

mPEG2000-DSPE:
18:0 PEG2000 PE:1,2-distearoyl-
sn
-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)