商品编号


F30204B-D



品牌


FormuMax



公司


FormuMax Scientific Inc



公司分类


Doxoves?-Liposomal Doxorubicin HCl



Size

2 mL

商品信息

Doxoves? -? PEGylated
Liposoma
l Doxorubicin HCl

Doxorubicin HCl is loaded into PEGylated
liposomes
composed of HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol) with ammonium gr
ADI
ent by the active lo
ADI
ng approach. It is comparable to the commercial product DOXIL?. ?The
liposomes
are prepared to very high quality with consistent lot-lot characteristics. Narrow particle size distribution and high drug encapsulation efficiency.??Note the high drug concentration (4mg/mL compared to 2 mg/mL for DOXIL?)? allows the researchers to perform experiments at higher concentration/doses.

?

Product For Research only and NOT for Human Use
?

Specifications

Product code: F30204B-D

Lipid composition:
? HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3
mol/mol)

Lipid concentration
:? 40.0 mM

Doxorubicin
HCl:
? 4.0 mg/mL

Encapsulation efficiency:
> 95% (typically 98%)

Lo
ADI
ng battery:?
250 mM?ammonium sulfate

Mean particle size:
? 85 nm (80 - 90 nm)

External solution:
? 10% sucrose, 10 mM histidine, pH 6.5

Shelf-life:
?6 months, storage:?2-8 degree C

?

HSPC:
hydrogenated phosphatidylcholine (Soy)

CHOL:
cholesterol

mPEG2000-DSPE:
18:0 PEG2000 PE:1,2-distearoyl-
sn
-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]