Background: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Host species/Isotype: Rabbit/IgG

Species reactivity: Human, Mouse, Rat

Immunogen: KLH conjugated synthetic peptide derived from mouse CD68.

 Storage instructions: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Concentration:1mg/ml

Purity: affinity purified by Protein A

Clonality: Polyclonal

Molecular weight: 37KDa

Tested applications:

WB=1:500-2000

ELISA=1:500-1000

IHC-P=1:100-500

IHC-F=1:100-500

Flow-Cyt=1μg/Test

ICC=1:100-500

IF=1:200-800