商品编号


LS002829



品牌


Worthington



公司


Worthington Biochemical Corporation



公司分类


Products



Size

100 mg

商品信息
Trypsin Inhibitor, Lima BeanSource: Lima BeanFraction III of the preparation described by Fraenkel-Conrat, et al., Arch. Biochem. Biophys., 37, 393 (1952). Supplied as a dialyzed, lyophilized powder.Store at 2-8°C.N/A
Lima Bean Inhibitor
: Lima bean trypsin inhibitor which inhibits bovine as well as human trypsin and plasmin, acts upon both trypsin and chymotrypsin by forming equimolar complexes. Lima bean inhibitors may be chromatographically separated into as many as six variants. Jones
et al., Biochem., 2
, 66, (1963) characterized four of them. All have similar but not identical amino acid composition, contain six or seven disulfide bonds and lack methionine and tryptophan. Molecular weights vary between 8 kDa and 10 kDa.
St
ABI
lity/Storage:
The lima bean inhibitor is stable 1-2 years at 2-8°C.
Ovomucoid
: Ovomucoids are the glycoprotein protease inhibitors of avian egg white. There are several protease inhibitors in egg white. The
Worthington
product is that described by Lineweaver and Murray
JBC, 171
, 565 (1947). It has a molecular weight of approximately 28 kDa.
St
ABI
lity/Storage:
Ovomucoid is stable 1- 2 years when stored at 2-8°C.
Pancreatic Inhibitor
: The pancreatic inhibitor produced by
Worthington
is often referred to as the Kunitz inhibitor and was first crystallized by Kunitz and Northrop
J. Gen. Physiol., 19
, 991 (1936). It forms a very stable 1:1 complex with bovine trypsin between pH 3 and 10 and also with human trypsins. Chymotrypsin is also inhibited by this product but is bound less tightly. The esterolytic, proteolytic and elastolytic activities of porcine elastase, on the other hand, are not inhibited. The Kunitz inhibitor is a single polypeptide chain of 58 amino acids and has a molecular weight of 6.5 kDa. When lung tissue is used as the source, the inhibitor is called aprotinin.
St
ABI
lity/Storage:
The pancreatic inhibitor is stable 1-2 years when stored at 2-8°C.
Soybean Inhibitor
: The soybean trypsin inhibitor was first crystallized by Kunitz in 1945 and is one of several such inhibitors found in soybeans. Its molecular weight is 21,500 ± 800 daltons and the optimum pH is 7.0. Soybean inhibitor inhibits trypsin mole-for-mole and to a lesser extent chymotrypsin.
St
ABI
lity/Storage:
The soybean inhibitor is stable for 1-2 years at 2-8°C.
Unit Definition
: The activity of the inhibitors is expressed as the amount of twice crystallized trypsin (
Worthington
Code: TRL) inhibited per milligram of inhibitor. 1mg TRL ≥180 TAME units, 10,350 BAEE units, 3,450
USP
/NF units.

Related Products:

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