商品编号


F1420



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


Inhibitors



Size

5 mg

商品信息

A potent, revers
IBL
e, cell permeable and specific inhibitor of ATPase of p97 (also called valosin-containing protein (VCP)) with IC50 of 1.5 μM. DBeQ inhibits both ubiquitin-dependent and autophagic protein degradation pathways and rapidly induces caspases -3 and -7 activity and apoptosis.

Additional Information






Product Name:

DBeQ



Also Known As:

N?, N?-Dibenzylquinazoline-2,4-diamine; CAS# 177355-84-9; C??H??N?



Catalog No.:

F1420



Size:

5 mg



Molecular Weight:

340.42 Da



Species:

N/A



Source:

Synthetic



Stock:

Powder



Concentration:

N/A



Quality Assurance:

≥ 98% by HPLC



Storage:

Elig
IBL
e for room temperature shipping. Store at -20°C upon receiving; protect from air and light



PDF Data Sheet:

PDF Datasheet



NCBI RefSeq:

N/A



Image(s):

N/A



Shipping Method:

Room temperature shipping



References:

1. Chou TF,
et al
. (2011) Proc Natl Acad Sci U S A, 108(12), 4834-4839.?
2. Chou TF,
et al
. (2011) Autophagy, 7(9), 1091-1092.?




Details

A potent, revers
IBL
e, cell permeable and specific inhibitor of ATPase of p97 (also called valosin-containing protein (VCP)) with IC50 of 1.5 μM. DBeQ inhibits both ubiquitin-dependent and autophagic protein degradation pathways and rapidly induces caspases -3 and -7 activity and apoptosis.