商品编号


H6110



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


Deubiquitinating Enzymes



Size

25 ?g

商品信息

Deubiquitinating enzymes (DUBs) are proteases that posses the
ABI
lity to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play important roles in regulating various cellular events.
USP
11 belongs to the ubiquitin-specific protease family. It helps in repairing DNA damage. It has been found to interact with RanBPM, a RanGTP-binding protein.UHX1

Additional Information






Product Name:

GST-
USP
11



Also Known As:

UHX1



Catalog No.:

H6110



Size:

25 ?g



Molecular Weight:

109.8 kDa



Species:

Human



Source:

Sf9 insect cells



Stock:

20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol



Concentration:

See tube label



Quality Assurance:

~85% by SDS-PAGE, see datasheet for gel image



Storage:

Store at -80°C; avoid multiple freeze-thaw cycles



PDF Data Sheet:

PDF Datasheet
，
MSD
S



NCBI RefSeq:

NM_004651



Image(s):

N/A



Shipping Method:

Dry ice shipping



References:

1. Wanson DA,
et al
. (1996) Hum Mol Genet 5, 533 – 538.
2. Ideguchi H,
et al
. (2002) Biochem J 367(Pt 1), 87 – 95. 3. Reyes-Turcu FE,
et al
.(2009) Annu Rev Biochem 78, 363 – 397.




Details

Deubiquitinating enzymes (DUBs) are proteases that posses the
ABI
lity to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play important roles in regulating various cellular events.
USP
11 belongs to the ubiquitin-specific protease family. It helps in repairing DNA damage. It has been found to interact with RanBPM, a RanGTP-binding protein.