商品编号


H5910



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


Deubiquitinating Enzymes



Size

25 ?g


商品信息

USP
9X belongs to the ubiquitin-specific protease (
USP
) family.
USP
9X has been found to deubiqitinate more than a dozen of substrates including mcl1, survivin, SMAD4, SMN and Itch.
USP
9X is located on the X chromosome, but it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Also,
USP
9X is unregulated in various cancers. The catalytic domain contains the region from amino acid 1531 to amino acid 1972.

Additional Information






Product Name:

GST-
USP
9X(catalytic domain)



Also Known As:

AXAM2; SMT3IP2



Catalog No.:

H5910



Size:

25 ?g



Molecular Weight:

51 kDa



Species:

Human



Source:

Bacterial recombinant



Stock:

20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol



Concentration:

See tube label



Quality Assurance:

~ 80% by SDS-PAGE, see datasheet for gel image



Storage:

Store at -80°C; avoid multiple freeze-thaw cycles



PDF Data Sheet:

PDF Datasheet
，
MSD
S



NCBI RefSeq:

NM_021627.2



Image(s):

(Click image to enlarge)








Coomassie-stained SDS-PAGE
Lane 1: Molecular weight
Marker
s
Lane 2: 5 ?g purified GST-
USP
X (catalytic domain)







Shipping Method:

Dry ice shipping



References:

Homan CC,
et al.
(2014) Am J Hum Genet. 94(3):470-8.




Details


USP
9X belongs to the ubiquitin-specific protease (
USP
) family.
USP
9X has been found to deubiqitinate more than a dozen of substrates including mcl1, survivin, SMAD4, SMN and Itch.
USP
9X is located on the X chromosome, but it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Also,
USP
9X is unregulated in various cancers. The catalytic domain contains the region from amino acid 1531 to amino acid 1972.

Images:
(Click image to enlarge)








Coomassie-stained SDS-PAGE
Lane 1: Molecular weight
Marker
s
Lane 2: 5 ?g purified GST-
USP
X (catalytic domain)