商品编号


H1100



品牌


UBPBio



公司


Ubiquitin-Proteasome Biotechnologies, LLC



公司分类


Deubiquitinating Enzymes



Size

25 ?g

商品信息

Deubiquitinating enzymes (DUBs) are proteases that posses the
ABI
lity to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play important roles in regulating various cellular events. UCHL1 is one of the four members of the ubiquitin C-terminal hydrolase (UCH) family. It is thought to be mainly involved in cleaving proubiquitin proteins into monomeric ubiquitin.

Additional Information






Product Name:

UCHL1



Also Known As:

PARK5; PGP95; PGP9.5; Uch-L1; PGP 9.5



Catalog No.:

H1100



Size:

25 ?g



Molecular Weight:

24.8 kDa



Species:

Human



Source:

Bacterial recombinant



Stock:

20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol



Concentration:

See tube label



Quality Assurance:

~95% by SDS-PAGE, see datasheet for gel image



Storage:

Store at -80°C; avoid multiple freeze-thaw cycles



PDF Data Sheet:

PDF Datasheet
，
MSD
S



NCBI RefSeq:

NM_004181



Image(s):

N/A



Shipping Method:

Dry ice shipping



References:

1. Pickart CM,
et al.
(1985) J Biol Chem 260(13), 7903 – 7910.
2. Wilkinson KD (1997) FASEB J 11(14), 1245 – 1256. 3. Larsen CN,
et al.
(1998) Biochemistry 37(10), 3358 – 3368.
4. Reyes-Turcu FE,
et al.
(2009) Annu Rev Biochem 78, 363 – 397.




Details

Deubiquitinating enzymes (DUBs) are proteases that posses the
ABI
lity to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play important roles in regulating various cellular events. UCHL1 is one of the four members of the ubiquitin C-terminal hydrolase (UCH) family. It is thought to be mainly involved in cleaving proubiquitin proteins into monomeric ubiquitin.