商品编号


AG-20A-0045-C050



品牌


Adipogen



公司


Adipogen



公司分类


Antibodies



Size

50 ?g


商品信息


More Information



Product Details



Synonyms

Visceral
ADI
pose Tissue-derived Serine Protease Inhibitor; Serpin A12; OL-64



Product Type

Monoclonal Antibody



Properties



Clone

VP63



Isotype

Mouse IgG1κ



Immunogen/Antigen

Recombinant human vaspin.



Application


ELISA
:
(direct or indirect: 1:2'000-1:5'000)

Immunohistochemistry:
frozen sections (1:100)
Western blot:
(1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature).
Optimal conditions should be determined individually for each application.



Crossreactivity

Human



Specificity

Recognizes human vaspin. Detects a band of ~48kDa by Western blot.



Purity Detail

Protein G-affinity purified.



Concentration

1mg/ml



Formulation

Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.



Use/St
ABI
lity

Stable for at least 1 year after receipt when stored at -20°C.



Documents



MSD
S


Download PDF



Product Specification Sheet



Datasheet


Download PDF





Vaspin (Visceral
ADI
pose tissue-derived serpin; Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing
ADI
pocytokine that has been isolated from both visceral and subcutaneous white
ADI
pose tissue. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and was found to be correlated with various metabolic parameters. Vaspin may represent a novel bio
Marker
for obesity and impaired insulin sensitivity and might serve as a new therapeutic target of metabolic syndrome.


Product References

Central vaspin admi
NIST
ration acutely reduces food intake and has sustained blood glucose-lowering effects: N. Kl?ting, et al.; Diabetologia
54,
1819 (2011)

Untersuchungen zur Rolle von Vaspin in der Psoriasis: K. Rall; Diss. Universit?t Leipzig (2012) (IHC protocol)