商品编号


JP28141



品牌


IBL



公司


IBL,inc



公司分类


Antibodies


商品信息

Quantity / Tests
100 ?g
Species / Antigen
Synthetic peptide in the C terminus of human CAD
Host
Rabbit
Subclass / Clone
IgG
Type
Polyclonal
Purification
Affinity purified with antigen peptide
Label
No
Regulatory Status:
For research use only


Details for:


?
Anti-Human CAD (2194) Rabbit IgG

mTOR is the target molecule of rapamycin (trade name: Sirolimus) in mammals and it has been recognized as a central molecule in the signaling pathway regulating proliferation and cell growth. Since DNA replication is also essential for proliferation, regulation of cell growth and amino-acid perception it is also centrally related to mTOR and deeply involves in the biosynthesis of nucleic acids.
CAD (carbamoyl phosphate synthetase, aspartate transcarbamoylase, dihydroorotase) was discovered as a result of a survey for molecules that are related to nucleic acid biosynthesis in a molecular complex with raptor and mLST8. CAD has an important role in the pathway of pyrimidine biosynthesis. CAD is an enzyme that catalyzes the pyrimidine biosynthesis and itself is regulated by phosphorylation of other protein kinases.
mLST8 bridges between CAD and mTOR and CAD plays a role as a signaling molecule in the mTOR pathway by a cross-interaction with mLST8.
This antibody is considered as a useful tool for research in the mTOR signaling pathway, especially for research in the regulation system of nucleic acid biosynthesis.

Distributed by
IBL
International

For concrete data please consult the Instruction for Use in the download box on the right side.