商品编号


3470-096-K



品牌


Trevigen



公司


Trevigen, Inc



公司分类


Cell Based Assays



Size

96 Wells

商品信息

Description

The Cultrex?
In Vitro
Angiogenesis Assay Tube Formation Kit was developed for the evaluation?of inducers and inhibitors of endothelial cell tube formation. ?During the course of the assay, endothelial cells are seeded on a thick gel of Basement Membrane Extract in the presence of angiogenesis modulating agents. ?If the medium is permissive to the angiogenic response, cells will self assemble into tube networks within hours; if there are inhibitors in the medium, tube network formation will be incomplete or nonexistent. Sulforaphane [1- isothiocyanato-(4R)- methylsulfinyl)-butane], found in broccoli and other cruciferous vegetables, is a naturally occurring cancer chemopreventive agent, and is provided as a control inhibitor to visualize this process. ?Endothelial cells may be fluorescently labeled using Calcein AM, and images captured using a microscope camera may be analyze to quantify the angiogenic response.?Cultrex
?

In Vitro
Angiogenesis Assay Kit provides a cost-effective method for investigation of
Prospec
tive angiogenesis inhibitors in a 96 well plate format.




Catalog # 3470-096-K includes :



Catalog Number

Description

Qty



3470-096-01

Cell Staining Solution

1



3433-005-01

Cultrex? BME, reduced growth factor without phenol red

1



3470-096-02

Sulforaphane

1



4892-010-01

Calcein AM

1




Syndecan-4 Is a Major Syndecan in Primary Human Endothelial Cells In Vitro, Modulated by Inflammatory Stimuli and Involved in Wound Healing
Tram Thu Vuong, Trine M. Reine, Amanda Sudworth, Trond G. Jenssen, and Svein O. Kolset
Journal of Histochemistry & Cytochemistry, Feb 2015; 10.1369/0022155415568995
http://jhc.sagepub.com/cgi/content/abstract/0022155415568995v2

Gastric tumour-derived ANGPT2 regulation by DARPP-32 promotes angiogenesis
Zheng Chen, Shoumin Zhu, Jun Hong, Mohammed Soutto, DunFa Peng, Abbes Belkhiri, Zekuan Xu, and Wael El-Rifai
Gut, Mar 2015; 10.1136/gutjnl-2014-308416.
http://gut.bmj.com/cgi/content/abstract/gutjnl-2014-308416v1

“The Role of Angiogenesis in the Persistence of Chemoresistance in
Epithelial Ovarian Cancer”
“Osama Nusrat, Jimmy Belotte, Nicole M. Fletcher, Ira Memaj, Mohammed G. Saed, Michael P. Diamond,
and Ghassan M. Saed”
Reproductive Sciences, Nov 2016; 23: 1484 – 1492
http://rsx.sagepub.com/cgi/content/abstract/23/11/1484