商品编号


AG-CP3-0007-M001



品牌


Adipogen



公司


Adipogen



公司分类


Cancer



Size

1 mg


商品信息


More Information



Product Details



Synonyms

Q-Val-Glu-OPh; pan-Caspase Inhibitor (Negative Control); N-(2-Quinolyl)-L-valyl-L-glutamyl-(2,6-difluorophenoxy) methylketone



Product Type

Chemical



Properties



Formula

C
27
H
27
F
2
N
3
O
6




MW

527.5



Source/Host Chemicals

Synthetic.



Purity Chemicals

≥95% (TLC)



Appearance

White solid.



Solubility

Soluble in DMSO.



InChi Key

AXCYQC
BD
FVOWSL-JWIMYKKASA-N



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

Keep cool and dry.



Use/St
ABI
lity

Stable for at least 3 years after receipt when stored at -20°C.



Documents



MSD
S


Download PDF



Product Specification Sheet



Datasheet


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Cell permeable, non-toxic negative control for the caspase inhibitor Q-VD-OPh (Prod. No. AG-CP3-0006).

Stable in aqueous environment.

Several folds less inhibitory activity than Q-VD-OPh.

Perfect for both
in vitro
and
in vivo
studies.



Product References

Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties: T.M. Caserta, et al.; Apoptosis
8,
345 (2003)

The role of caspases in Alzheimer's disease; potential novel therapeutic opportunities: T.T. Rohn; Apoptosis
15,
1403 (2010)

Q-VE-OPh, a Negative Control for O-Phenoxy-Conjugated Caspase Inhibitors: B. Southerland, et al.; J. Cell Death
3,
33 (2010)

The pan-caspase inhibitor Q-VD-OPh has anti-leukemia effects and can interact with vitamin D analogs to increase HPK1 signaling in AML cells: X. Chen-Deutsch, et al.; Leuk. Res.
36,
884 (2012)